Alternative research methods and techniques

Literature Search for Alternatives Worksheet step-by-step approach to an alternatives search provides guidance and resources to facilitate gathering information on alternatives to the use of research animals.

Go3R is a knowledge-based or 'semantic' search engine for alternative methods to animal experiments. Users are able to search PubMed, TOXNET or the World Wide Web using a Google search with automatic higher ranking of 3Rs relevant websites. Searches are presented to the user alongside a dynamic table of contents which highlights 3Rs information, allowing the quick and easy selections of relevant documents.

EUROECOTOX database of bioassays is a database of alternative and standard assays in ecotoxicological testing.

The EURL ECVAM Search Guide provides guidance on how to undertake a comprehensive search for high quality information on alternatives to the use of animals in research. It includes an inventory of relevant resources, a check list to allow users to undertake searches in a structured and systematic manner, search principles, information on how to document searches, suggested search terms etc.

ALTBIB: Alternatives to Animal Testing is a database search tool which enables users to find publications on PubMed/Medline which provide information on alternatives to the use of live vertebrates in biomedical research and testing

Adverse Outcome Pathways, Molecular Screening and Toxicogenomics is a collection of validated Adverse Outcome Pathways (AOPs).